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Rashid Deane Selected Research

Low Density Lipoprotein Receptor-Related Protein-1 (LDL-Receptor Related Protein)

10/2012Low-density lipoprotein receptor-related protein 1: a physiological Aβ homeostatic mechanism with multiple therapeutic opportunities.
9/2012Low-density lipoprotein receptor overexpression enhances the rate of brain-to-blood Aβ clearance in a mouse model of β-amyloidosis.
1/2011Impaired lipoprotein receptor-mediated peripheral binding of plasma amyloid-β is an early biomarker for mild cognitive impairment preceding Alzheimer's disease.
9/2005Role of the MEOX2 homeobox gene in neurovascular dysfunction in Alzheimer disease.
11/2004RAGE (yin) versus LRP (yang) balance regulates alzheimer amyloid beta-peptide clearance through transport across the blood-brain barrier.

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Rashid Deane Research Topics

Disease

19Alzheimer Disease (Alzheimer's Disease)
12/2014 - 05/2004
5Dementia (Dementias)
12/2014 - 07/2003
4Sleep Deprivation
12/2017 - 01/2015
4Cognitive Dysfunction
12/2014 - 11/2004
3Cerebral Amyloid Angiopathy (Congophilic Angiopathy)
01/2016 - 04/2007
3Traumatic Brain Injuries (Traumatic Brain Injury)
01/2015 - 05/2012
3Amyloidosis
09/2012 - 08/2004
2COVID-19
11/2021 - 01/2021
2Neurodegenerative Diseases (Neurodegenerative Disease)
12/2014 - 05/2013
2Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease)
11/2009 - 04/2008
2Hemorrhage
03/2009 - 11/2006
1Neurologic Manifestations (Neurological Manifestations)
01/2021
1Gliosis
01/2014
1Amyloid Plaque
09/2012
1Down Syndrome (Down's Syndrome)
05/2012
1Brain Diseases (Brain Disorder)
04/2012
1Hypoxia (Hypoxemia)
11/2010
1Disease Progression
11/2009
1Infarction (Infarctions)
03/2009
1Nervous System Diseases (Neurological Disorders)
01/2009
1Brain Ischemia (Cerebral Ischemia)
11/2006
1Intracranial Hemorrhages (Intracranial Hemorrhage)
11/2006
1Stroke (Strokes)
11/2006
1Embolic Stroke
11/2006
1Ischemic Stroke
11/2006
1Cerebrovascular Disorders (Cerebrovascular Occlusion)
11/2004
1Neuroinflammatory Diseases
11/2004

Drug/Important Bio-Agent (IBA)

10Amyloid beta-PeptidesIBA
10/2012 - 07/2003
9Amyloid (Amyloid Fibrils)IBA
01/2016 - 11/2004
7Proteins (Proteins, Gene)FDA Link
01/2021 - 08/2004
5Peptides (Polypeptides)IBA
05/2013 - 12/2010
5Low Density Lipoprotein Receptor-Related Protein-1 (LDL-Receptor Related Protein)IBA
10/2012 - 11/2004
3Biomarkers (Surrogate Marker)IBA
06/2017 - 01/2011
3LDL Receptors (LDL Receptor)IBA
09/2012 - 08/2004
3AnticoagulantsIBA
11/2009 - 11/2006
2Apolipoproteins E (ApoE)IBA
12/2017 - 12/2016
2Protein Isoforms (Isoforms)IBA
12/2017 - 12/2016
2tau Proteins (tau Protein)IBA
12/2014 - 01/2014
2Superoxide Dismutase-1IBA
11/2009 - 04/2008
2Protein CIBA
01/2009 - 11/2006
2Serine Proteases (Serine Protease)IBA
01/2009 - 11/2006
1AntibodiesIBA
11/2021
1hemagglutinin esteraseIBA
01/2021
1Lactic Acid (Lactate)FDA LinkGeneric
06/2017
1Phosphopyruvate Hydratase (Enolase)IBA
01/2015
1Protein AggregatesIBA
12/2014
1Cell Surface ReceptorsIBA
10/2012
1ApolipoproteinsIBA
09/2012
1Apolipoprotein E4IBA
05/2012
1FPS-ZM1IBA
04/2012
1Lipoprotein Receptors (Lipoprotein Receptor)IBA
01/2011
1Blood Proteins (Serum Proteins)IBA
11/2010
1Hemoglobins (Hemoglobin)IBA
03/2009
1OccludinIBA
04/2008
1Tight Junction ProteinsIBA
04/2008
1Claudin-5IBA
04/2008
1NeurotoxinsIBA
04/2007
1Tissue Plasminogen Activator (Alteplase)FDA Link
11/2006
1NF-kappa B (NF-kB)IBA
11/2006
1Matrix Metalloproteinase 9 (Gelatinase B)IBA
11/2006
1PAR-1 ReceptorIBA
11/2006
1Immunoglobulin G (IgG)IBA
12/2005
1Member 1 Subfamily B ATP Binding Cassette TransporterIBA
11/2005
1Forkhead Transcription Factors (Forkhead Box Proteins)IBA
09/2005
1Receptor for Advanced Glycation End ProductsIBA
11/2004
1Advanced Glycation End ProductsIBA
11/2004
1Proteasome Endopeptidase Complex (Proteasome)IBA
08/2004

Therapy/Procedure

2Therapeutics
03/2009 - 11/2006
1Thrombolytic Therapy
11/2006